A powerful tool for mapping of short reads onto a reference genome
Introducing novoAlign, a powerful tool for mapping short reads onto reference genomes from Illumina and MGI Tech platforms. Designed to streamline and optimize this critical process, novoAlign ensures precise alignments and deeper genetic insights. Elevate your research and unlock data potential with our advanced technology.
Trusted by more than 200 institutions, research centers, universities, and corporations
Why novoAlign
novoAlign+GATK pipeline scores a higher AUC value, higher recall, and higher precision than BWA+GATK
High AUC for SNPs
ROC-like PR curves from hap.py results comparing GIAB benchmark SNPs with Novoalign+GATK and BWA+GATK pipeline SNPs. The graph focuses on high-quality SNPs, and the AUC value is calculated using the “bayestestR” library in R.
High AUC for INDELs
ROC-like PR curves from hap.py results comparing GIAB benchmark INDELS with Novoalign+GATK and BWA+GATK pipeline INDELs. The graph focuses on high-quality INDELs, and the AUC value is calculated using the “bayestestR” library in R.
Why novoAlign
Superior Precision and Recall for Structural Variants
Achieve unparalleled accuracy in detecting variants with our novoAlign, delivering superior precision and recall rates. Whether identifying deletions, duplications, or structural variants, novoAlign ensures reliable results, minimizing false positives and capturing critical genomic alterations with confidence.
High sensitivity
Unlocking Precision: High Sensitivity in Sequence Alignment
Discover the power of high sensitivity in sequence alignment. Our advanced aligner, novoAlign, ensures precision and accuracy in your genomics and bioinformatics projects, providing a detailed view of your data. No more missed variations or incomplete alignments.
This figure is obtained from a study on reads alignment or contigs assembly against a large reference genome. It shows that novoAlign has scored highest in sensitivity compared to other aligners. (Source: https://doi.org/10.48550/arXiv.1303.3997)
Technical support
Fully backed up by extensive technical support
We give you the assurance and confidence in your research needs. Explore, and post questions in our information rich support forum to seek the best answers to all your technical questions from a community of experts and fellow users.
How novoAlign Works
novoAlign streamlines your genomic analysis from start to finish. It begins with NGS data and a reference genome, then performs precise read alignment, followed by variant calling and annotation. The process concludes with variant selection and validation assessment, ensuring accurate and reliable results for your research.
Testimonial
“novoAlign showed the highest accuracy in all alignments. It is also reached the best mapping score for uniquely aligned coding sequences in WGS analysis”
Neural Computing and Applications, 32(22), 15669-15692 (2021)
Other unsurpassed features
Applications
Unleashing novoAlign in diverse applications
Publications
What others are saying?
“GATK worked best on alignments produced by novoAlign.”
“novoAlign + GATK detects more variants than the other.”
“We observed that Novoalign was the leading aligner with the highest accuracy.”
Unlocking the potentials in various research areas
novoAlign can be used in numerous fields in the biological sciences.
Genomics
Transcriptomics
Metagenomics
Pharmacology
Cancer Research
Human Genetics
Plant Genomics
