A 25-35% performance improvement for mate pair alignments when using long & short fragment length option -i MP 99[-|,]99 99[-|,]99

This release is primarily about better UMI support with changes in Novoalign for extracting UMIs from 5′ of read and changes in Novosort to implement UMI clustering and correction algorithms similar to that in UMI-Tools, including consensus read generation, at blazingly fast speeds.

Release V4.02.01.1 and V4.02.03 of Novoalign have just be added to our website for download. These updates fix an assert failure during soft clipping of alignments. We had a s single report of an assert failure that occurred when a part of chimeric read aligned 1bp over the end of an unplaced contig.

Release Novosort (V1.03.05) Fix: When sorting BWA MEM alignments novosort may stop with error “Mate Read not found”. This happens when BWA MEM reports a secondary alignment for a pair where mate is not mapped and the secondary alignment RNEXT & PNEXT are set to secondary alignment location rather than the primary alignment location as […]

The final Developer conference of 2014 was held in Illumina’s new corporate space in Mission Bay, San Francisco. Over 70 people learned from developers who have successfully partnered with BaseSpace, as well as the very latest from the Illumina team. Our Bioinformatics Director Zayed Albertyn was invited to share about his experience on our top […]

The 4th International Plantation Industry Conference & Exhibition was organized by the International Institute of Plant Management and Universiti Teknologi Mara. The 2 day event was held at the heart of Borneo island and the land of Kenyalang, Kuching Sarawak. Among the participants are large players in the plantation industry such as MPOB, MRB, MCB, […]