A 25-35% performance improvement for mate pair alignments when using long & short fragment length option -i MP 99[-|,]99 99[-|,]99
This release is primarily about better UMI support with changes in Novoalign for extracting UMIs from 5′ of read and changes in Novosort to implement UMI clustering and correction algorithms similar to that in UMI-Tools, including consensus read generation, at blazingly fast speeds.
Release V4.02.01.1 and V4.02.03 of Novoalign have just be added to our website for download. These updates fix an assert failure during soft clipping of alignments. We had a s single report of an assert failure that occurred when a part of chimeric read aligned 1bp over the end of an unplaced contig.
Novocraft Technologies Sdn. Bhd. today announced the worldwide release of NovoWorx™, it’s first Genome Data Management and Analytics Platform. NovoWorx™ is a comprehensive Next Generation Sequencing (NGS) data management and analytics platform to meet the growing need for working with large sequencing datasets. Offering a combination of unique proprietary and third-party software, the platform […]
Release Novosort (V1.03.05) Fix: When sorting BWA MEM alignments novosort may stop with error “Mate Read not found”. This happens when BWA MEM reports a secondary alignment for a pair where mate is not mapped and the secondary alignment RNEXT & PNEXT are set to secondary alignment location rather than the primary alignment location as […]
